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Estrogens may play a role, not only in classical endocrine-related tumors, such as breast or prostate, but also in several other human nosological entities, including neurodegenerative disorders, cardiovascular and immune-related diseases. This volume focuses on topics ranging from the impact of endogenous and exogenous estrogens on human development and cancer risk, to novel aspects in mechanisms of estrogen action, to estrogen implication in human malignancies (breast, prostate, liver), to the emerging role of estrogen in neurodegenerative disorders (Alzheimer's disease, multiple sclerosis, Parkinson's disease), to estrogen action in the cardiovascular system (including both genomic and nongenomic), to estrogen effects on cells of the immune system and their relevance to immune response and autoimmune diseases. The resulting inferences for clinics, diagnosis, prognosis, and treatment are also presented and extensively discussed.--Publisher's website.
This volume investigates the multifaceted role of estrogens in a wide spectrum of human diseases beyond traditional endocrine-related cancers. The book examines how endogenous and exogenous estrogens influence human development and cancer risk, explores new mechanisms of estrogen action, and details their implication in malignancies such as breast, prostate, and liver cancer. Furthermore, it delves into the emerging connections between estrogen and neurodegenerative disorders like Alzheimer's, multiple sclerosis, and Parkinson's disease, as well as estrogen's effects on the cardiovascular system and immune cells, including their relevance to immune response and autoimmune diseases. The work concludes by presenting and discussing clinical inferences for diagnosis, prognosis, and treatment.
This comprehensive volume is structured to provide detailed insights into the complex relationship between estrogens and various human diseases. The scope ranges from established links in endocrine-related cancers to emerging roles in neurodegenerative and cardiovascular conditions. The inclusion of clinical implications suggests a focus on practical applications for healthcare professionals. The depth and breadth of topics covered indicate a text intended for researchers and clinicians seeking an authoritative overview of current knowledge in the field.
Page Count:
551
Publication Date:
2006-01-01
ISBN-10:
1573316695
ISBN-13:
9781573316699
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