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The development of devices that incorporate biological assemblies is impacting analytical and biomedical research. Today, scientists can monitor vital biological interactions-such as the binding of DNA to proteins-in real time, deriving unique information necessary to understanding biochemical pathways and thus aiding the design of drugs to regulate these processes. Biomolecular Sensors describes the development of this new technology covering the fundamental physics through to applications. The principles of biological recognition, immobilization techniques, and transducer technology are described in depth in order to provide the necessary background to readers from various disciplines. Focusing on the study of antigen-antibody, DNA-protein and receptor-ligand binding events, the book covers biological applications and describes the commercial instruments available to exploit this technology in areas as diverse as biological research, medical applications and environmental monitoring. With contributions from internationally recognized experts, this is the essential reference for advanced undergraduates and postgraduates as well as professionals in this rapidly advancing field.
This volume investigates the development and application of devices that integrate biological assemblies to monitor vital molecular interactions in real time. Edited by Christopher R. Lowe and Electra Gizeli, the text synthesizes contributions from international experts to bridge the gap between fundamental physical principles and practical biomedical implementation. It provides a comprehensive framework for understanding how these sensors facilitate drug design and biochemical pathway analysis through the study of binding events.
What You Will Find
Experts identify this work as a foundational reference for advanced students and professionals working within the intersection of biology and engineering. Readers frequently note the technical density of the prose, which is designed to support interdisciplinary research in this rapidly evolving field.
Page Count:
336
Publication Date:
2002-01-01
Publisher:
Taylor & Francis, Inc.
ISBN-10:
0203212193
ISBN-13:
9780203212196
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