
Presenting a complete overview of the effects of steroid hormones in the brain and describing new methods for investigating these effects, this book discusses theories on steroid action in the central nervous system and the techniques for receptor localization and quantification and enzyme regulation. The author explores the use of transgenic/antisense strategies to determine sites and the cellular effects of steroid action in the brain. He covers steroid action on mood, cognition, sensorimotor action, neuroprotection, and plasticity, and describes methods using molecular, electrophysical, and behavioral techniques to link cellular mechanisms of steroid action with behavioral effects.
This text investigates the complex mechanisms by which neurosteroids modulate the central nervous system through their interaction with the GABA-A receptor. The author synthesizes current theories regarding steroid action in the brain, providing a comprehensive framework for understanding how these hormones influence neural pathways. By detailing both established and emerging research methodologies, the work bridges the gap between molecular cellular mechanisms and observable behavioral outcomes.
What You Will Find
Experts recognize this volume as a technical resource for researchers and students focusing on neuroendocrinology. Readers frequently note the academic density of the prose, which serves as a foundational reference for those studying the intersection of steroid chemistry and neurological plasticity.
Page Count:
408
Publication Date:
2003-01-01
Publisher:
CRC Press
ISBN-10:
0203508165
ISBN-13:
9780203508169
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