This text investigates the clinical methodologies and biochemical markers required to accurately evaluate the nutritional status of human subjects. Howerde E. Sauberlich, a recognized expert in nutritional biochemistry, synthesizes decades of laboratory research to provide a comprehensive framework for identifying deficiencies and metabolic imbalances. The work serves as a technical manual for clinicians and researchers, detailing the specific assays and diagnostic criteria necessary to interpret physiological data within a nutritional context.

Experts in the field of clinical nutrition identify this work as a foundational reference for laboratory diagnostics. Readers frequently note the high level of technical density, making it a primary resource for professionals and advanced students in medical and nutritional sciences.