This volume presents the proceedings of the 12th CIBA Vision Symposium, held in Osaka and Tokyo in November 1999. It focuses on advancements and discussions within the field of ophthalmology, as presented by leading researchers and practitioners.

As a supplement issue of the journal Ophthalmologica, this volume is intended for a specialized audience of ophthalmologists and researchers. The content likely comprises technical papers and clinical findings, reflecting the state of the art in ophthalmology as presented at the symposium. Its value lies in the specific, peer-reviewed research shared by experts in the field.