
Cytokines, a broad class of proteins, have a role in fighting infection and in mounting an immune response; in mediating cell differentiation and embryogenesis; in promoting cell growth; and in inhibiting growth or causing cell death. Recent advances in cell culture, monoclonal antibodies and recombinant DNA technology have made it possible to isolate these proteins and to obtain sufficient quantities to conduct clinical studies as well as laboratory experiments. Thus, the foundations have been laid for a new form of cancer therapy and for understanding how abnormalities in the cytokine network could contribute to the process of malignancy. Up-to-date and comprehensive, this book brings together current research and discusses it in the context of its present and potential clinical application. The book is intended for cancer researchers, clinical oncologists, and those involved in the pharmaceutical and biological product industries.
This book investigates the role of cytokines as a therapeutic modality in cancer treatment and the underlying mechanisms of the cytokine network in malignancy. Frances R. Balkwill, a researcher in the field of cancer biology, synthesizes data from cell culture, monoclonal antibody research, and recombinant DNA technology. The text provides a framework for understanding how these proteins can be isolated and applied in clinical settings to modulate immune responses or inhibit tumor growth.
What You Will Find
Scope Limits
Experts recognize this work as a foundational reference for oncologists and pharmaceutical researchers navigating the early clinical applications of cytokine therapy. Readers frequently note the technical density of the prose, which is tailored specifically for professionals within the biological product industries.
Page Count:
320
Publication Date:
1989-08-24
Publisher:
Oxford University Press
ISBN-10:
019261715X
ISBN-13:
9780192617156
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