Progress Toward Better Vaccines: Proceedings at a Meeting Organized by the WHO as Part of a Program for Vaccine Development Held in Bellagio, Italy, April 1985
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Author Description
The development of new or improved vaccines using biotechnological techniques is especially important for developing countries, where traditional means of vaccine manufacture are frequently not available. This volume explores the four main approaches for developing alternative vaccines: the use of live agents; the use of anti-idiotype antibodies; the introduction of DNA or cDNA coding for a protective antigen of the disease agent into a mammalian cell line, into a lower eukaryote, or into an appropriate bacterium; and the synthesis of oligopeptides corresponding to an epitope or a protective antigen of the disease agent.
Menrva's Summary
THE THESIS
This volume investigates the technical methodologies and strategic frameworks required to advance vaccine development for resource-limited regions through modern biotechnological innovation. The World Health Organization convened international experts to address the limitations of traditional vaccine manufacturing, proposing a shift toward advanced molecular techniques. The text synthesizes the consensus of this 1985 meeting, establishing a roadmap for utilizing genetic engineering and synthetic biology to combat infectious diseases in developing nations.
THE SCOPE MAP
What You Will Find
- Analysis of live agent utilization in vaccine production
- Methodologies for anti-idiotype antibody application
- Protocols for recombinant DNA and cDNA insertion into host cells
- Techniques for oligopeptide synthesis targeting specific protective antigens
Scope Limits
- The text does not cover clinical trial results for specific vaccines developed after 1985
- It excludes detailed manufacturing cost-benefit analyses for large-scale industrial implementation
THE AUTHORITY PERSPECTIVE
Experts recognize this publication as a foundational record of the early international effort to standardize biotechnological approaches to global immunization. Readers frequently note the technical density of the prose, which reflects the specialized nature of the scientific discourse present at the Bellagio meeting.
Page Count:
240
Publication Date:
1987-02-26
Publisher:
Oxford University Press
ISBN-10:
019261567X
ISBN-13:
9780192615671
Science
Vaccinology
Public Health
Vaccines
Medical
Biotechnology
Immunology
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