This text investigates the clinical efficacy and physiological mechanisms of psoralen compounds in the treatment of vitiligo. Authored by Abdel Monem El Mofty, a pioneer in the field of photochemotherapy, the work synthesizes decades of clinical observation and experimental data. It establishes the foundational framework for using psoralens in conjunction with ultraviolet light to stimulate repigmentation in patients suffering from localized or generalized vitiligo.

Experts recognize this work as a foundational text for understanding the development of PUVA therapy. Readers frequently note the historical significance of the research in shaping modern dermatological practices.