
Prior to the advent of rapid DNA sequencing in the late 90s, students were taught in depth about the physiology and ecology of microorganisms. There was a generally good understanding about the biology of each organism and how it interacted with its environment. Since then, the focus of research has shifted towards an analysis of nucleic acid sequences to determine possible cellular biochemistry or phylogeny. A microbial genome can now be sequenced in a matter of hours, and with the help of a panoply of software programmes the inner workings of the organism can be probed in great detail. However, there is now so much detail that the student or researcher tends to lose any sense of the underlying biology of their study organism. Microbiology has almost become a branch of molecular biology, with the biology getting lost in the molecular detail. This novel text reverses that trend by cutting through the molecular information overload and placing the new sequence-derived information in the context of the natural history of the organism in question. Each concise chapter has a fascinating and different story to tell, focussing on one pathogen or group of closely related pathogens and highlighting a particularly interesting and/or unusual feature. The aim is to abstract the relevant molecular and genomic information, and then to show how it provides insights into the biology of the organism as a whole. Microbiology of Infectious Disease is aimed at undergraduates, graduates, and researchers in microbiology, microbial ecology, disease ecology, and related areas. It is intended as a supplemental text for students to provide them with a detailed overview of the biology and natural history of the microorganisms they will routinely encounter and the factors that influence their pathogenicity and infectivity.
This text investigates how to reconcile the overwhelming influx of genomic sequence data with the foundational principles of microbial physiology and natural history. Author Sandy R. Primrose argues that modern microbiology has become overly focused on molecular detail at the expense of biological context. The book provides a framework for integrating rapid DNA sequencing results into a broader understanding of pathogen ecology, pathogenicity, and infectivity.
What You Will Find
Scope Limits
Experts identify this text as a corrective measure for students and researchers who feel overwhelmed by the sheer volume of molecular data in contemporary literature. Readers frequently note that the book successfully bridges the gap between high-level genomic analysis and the traditional biological study of microorganisms.
Page Count:
512
Publication Date:
2022-01-01
Publisher:
OUP Oxford
ISBN-10:
0192678841
ISBN-13:
9780192678843
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