This volume presents the proceedings of the 20th International Symposium on Bioinformatics Research and Applications (ISBRA 2024), a key event for the exchange of knowledge in the field. The symposium, held in Kunming, China, gathered researchers, developers, and practitioners to discuss advancements in bioinformatics and computational biology. This collection features 93 full papers, meticulously selected from 236 submissions, reflecting the rigorous review process and the breadth of topics covered.

This collection represents a significant compilation of current research in bioinformatics and computational biology, as evidenced by the rigorous selection process of its 93 papers from over 200 submissions. The symposium's focus on research and applications suggests a readership of academics and professionals seeking to stay abreast of the latest developments and practical implementations in the field. The proceedings are expected to offer a comprehensive overview of the state of the art, serving as a valuable resource for those engaged in this rapidly evolving scientific domain.