This text investigates the quantitative principles governing drug transport, reaction, and clearance within physiological systems to enable the rational design of advanced drug delivery materials. W. Mark Saltzman, a prominent researcher in biomedical engineering, synthesizes core concepts from polymer chemistry and physics to establish a rigorous framework for therapeutic delivery. The book provides a technical foundation for engineers and scientists tasked with developing synthetic materials that interact effectively with human biological environments. By integrating physical chemistry with physiological modeling, the author presents a methodology for predicting how drugs behave within the body.

Experts recognize this work as a foundational technical resource for students and professionals in biomedical engineering and pharmacology. Readers frequently note the high level of mathematical and scientific density, which requires a strong background in physical sciences to fully utilize the presented models.