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This volume describes the modulatory actions of neuropeptides and amines, comparing their role with new knowledge about L-glutamic acid and gamma-aminobutyric acid, the principal fast chemical neurotransmitters in mammalian brains. The discussions include changes in the ways chemical signalling is viewed following the discovery that multiple chemical signals may be secreted by single nerve cells. The impact of molecular genetics is also reviewed, including the discovery of increasing numbers of peptide signals. As an overview of the most recent advances in the field, this volume will interest students and researchers in the neurosciences and allied clinical fields.
This volume investigates the functional distinction and interplay between fast and slow chemical signaling mechanisms within the mammalian nervous system. The authors, E. C. Goodman and L. L. Iversen, synthesize emerging research to contrast the rapid transmission of neurotransmitters like L-glutamic acid and GABA with the modulatory actions of neuropeptides and amines. By examining the implications of co-secretion from single nerve cells and the influence of molecular genetics, the text provides a comprehensive framework for understanding complex neural communication.
What You Will Find
Experts and researchers in the neurosciences identify this text as a valuable synthesis of chemical signaling mechanisms. Readers frequently note the technical density of the prose, which serves as a foundational reference for those engaged in advanced clinical and biological study.
Page Count:
320
Publication Date:
1986-07-10
Publisher:
Oxford University Press
ISBN-10:
0198572166
ISBN-13:
9780198572169
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