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Under continual attack from both microbial pathogens and multicellular parasites, insects must cope with immune challenges every day of their lives. However, this has not prevented them from becoming the most successful group of animals on the planet. Insects possess highly-developed innate immune systems which have been fine-tuned by an arms race with pathogens spanning hundreds of millions of years of evolutionary history. Recent discoveries are revealing both an unexpected degree of specificity and an indication of immunological memory - the functional hallmark of vertebrate immunity. The study of insect immune systems has accelerated rapidly in recent years and is now becoming an important interdisciplinary field. Furthermore, insects are a phenomenally rich and diverse source of antimicrobial chemicals. Some of these are already being seriously considered as potential therapeutic agents to control microbes such as MRSA.Despite a burgeoning interest in the field, this is the first book to provide a coherent synthesis and is clearly structured around three broadly themed sections: mechanisms, interactions, and evolutionary ecology. This novel text adopts a truly interdisciplinary and concept-driven approach, integrating insights from immunology, molecular biology, ecology, evolutionary biology, parasitology, and epidemiology. It features contributions from an international team of leading experts who also describe the latest molecular immunological techniques.
This text investigates how insects have evolved sophisticated innate immune systems to survive constant microbial and parasitic threats while maintaining their status as the most successful animal group on Earth. The authors, Jens Rolffe and Stuart E. Reynolds, synthesize current research from immunology, molecular biology, and evolutionary ecology to explain the mechanisms behind insect immunity. By integrating data from parasitology and epidemiology, the book provides a framework for understanding the arms race between insects and pathogens over millions of years.
What You Will Find
Experts recognize this work as a foundational, interdisciplinary synthesis that bridges the gap between entomology and immunology. Readers frequently note the academic density of the prose, which serves as a primary resource for researchers and advanced students in the field.
Page Count:
272
Publication Date:
2009-08-31
Publisher:
Oxford University Press
ISBN-10:
0199551359
ISBN-13:
9780199551354
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