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The study of animal virus pathogenesis is an important and rapidly developing area, especially since the emergence of AIDS and the consequent increase in research activity. Because this work takes place at the interface between virology and immunology, understanding viral pathogenesis requires knowledge and use of techniques drawn from several disciplines. This book provides up-to-date coverage of the way that viral tropism, viral expression, and viral infectivity are assayed. It describes the identification of antiviral cytotoxic T cells, natural killer and free antibody responses. It also covers making vaccinia/viral cDNA for immunologic target recognition, and tissue and whole animal in situ hybridization.
This text investigates the complex mechanisms of animal virus pathogenesis by integrating techniques from virology and immunology to analyze viral behavior within host systems. Dr. Michael B. A. Oldstone, a prominent researcher in the field, provides a structured framework for laboratory investigation. The book addresses the critical need for standardized methodologies in studying viral tropism, expression, and infectivity, particularly in the context of emerging infectious diseases.
What You Will Find
Experts recognize this volume as a foundational technical resource for researchers operating at the intersection of virology and immunology. Readers frequently note the high level of technical detail, making it a standard reference for laboratory practitioners seeking to implement precise experimental assays.
Page Count:
192
Publication Date:
1990-01-01
Publisher:
IRL Press
ISBN-10:
0199631018
ISBN-13:
9780199631018
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