Author Description

Many different kinds of mutation can occur in a genome, from large-scale chromosomal rearrangements to small-scale point mutations. This range requires a variety of techniques to detect them; the most difficult is the point mutation, with several alternative techniques available, the suitability of each varying from gene to gene and laboratory to laboratory. This book covers the strategies behind, and methodologies of, mutation detection for the beginner. It will interest graduate students, technicians, and more experienced researchers and clinicians.