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Cell surface carbohydrates play critical roles in cell-cell interaction. In recent years, major advances have been made in understanding the molecular mechanisms of these processes. Genes encoding glycosyltransferases that synthesize unique oligosaccharides have been isolated, allowing the correlation of specific oligosaccharide structures with function. This book brings together leading researchers to describe our current knowledge in this important area of modern biology. Particular emphasis is given to cell-type-specific carbohydrate expression and the carbohydrates and proteins involved in cell recognition. Also included is a full discussion of key experimental approaches such as chemical synthesis and the three-dimensional structural analysis of carbohydrates.Molecular Glycobiology is a timely synopsis of this exciting and rapidly expanding field. It provides both an up-to-date description of the subject and leading researchers' views of likely future developments. As such, this volume will be invaluable for active researchers in glycobiology and medicine. However, its easily readable style will also appeal to non-specialists who need an authoritative but accessible text on this subject.
This volume investigates the molecular mechanisms governing cell surface carbohydrates and their critical role in mediating cell-cell interactions. Edited by Minoru Fukuda and Ole Hindsgaul, the text synthesizes contributions from leading researchers to correlate specific oligosaccharide structures with biological function. It provides a comprehensive framework for understanding how genes encoding glycosyltransferases influence carbohydrate expression and cellular recognition processes.
What You Will Find
Experts recognize this volume as a foundational reference for researchers in glycobiology and medicine. Readers frequently note that the text balances technical rigor with an accessible style suitable for both specialists and those entering the field.
Page Count:
280
Publication Date:
1994-09-15
Publisher:
Oxford University Press
ISBN-10:
0199633878
ISBN-13:
9780199633876
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