The Kiss of Death investigates Chagas' disease, a significant public health crisis affecting millions in Latin America and increasingly spreading globally. The book delves into the epidemiology, entomology, parasitology, pathology, and immunology of this protozoan-borne illness, caused by the triatomine bug. It examines current estimates of infection rates and discusses the challenges in treating the chronic stage of the disease, while also highlighting potential control measures through improved living conditions and hygiene. The text further addresses the disease's expansion beyond its traditional geographic boundaries due to migration and climate change.

The book is presented as a thorough study of Chagas' disease, addressing its status as a major public health problem. It covers various scientific disciplines involved in understanding and combating the illness, from epidemiology to immunology. The text also touches upon the disease's transmission and its growing presence outside of Latin America. The framing suggests a comprehensive overview for those interested in tropical diseases and public health.