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This Text Provides A Concise And Comprehensive Introduction To Key Immunotoxicological Issues For All Those Interested In, But With No Prior Knowledge Of, This Area Of Toxicology. The First Section Explores The Health Consequences Of Immunotoxicity, Namely The Adverse Effects Related To Chemically-induced Immunosuppression And Immunostimulation, Hypersensitivity Reactions And Autoimmune Diseases, With An Overview Of Major Immunotoxicants. The Second Part Describes The Latest Methods Used To Detect And Evaluate, Preclinically And Clinically, The Unexpected Immunotoxic Effects Of Xenobiotics. Trends In Implementing Strategies And Recent Changes To The Regulatory Aspects Are Also Considered. The Third Section Examines Possible Future Developments, Including In Vitro Methods, Biomarkers Of Immunotixicity And Risk Assessment.
This text investigates the fundamental principles and clinical implications of immunotoxicology, providing a framework for understanding how xenobiotics interact with the human immune system. Jacques Descotes, a recognized expert in the field, synthesizes complex toxicological data to bridge the gap between basic immunological science and practical regulatory application. The book serves as a foundational guide for professionals and students seeking to understand the mechanisms of chemically-induced immune dysfunction and the methodologies required for safety assessment.
What You Will Find
Experts and practitioners in the field of toxicology frequently cite this work as a primary resource for those entering the discipline. Readers note the clarity of the prose, which effectively distills complex regulatory and scientific concepts into an accessible format for non-specialists.
Page Count:
183
Publication Date:
2003-01-01
Publisher:
Taylor & Francis
ISBN-10:
0203362543
ISBN-13:
9780203362549
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