This volume presents cutting-edge research in the analysis of ophthalmic medical images. The 12th International Workshop on Ophthalmic Medical Image Analysis (OMIA 2025), held in conjunction with MICCAI 2025, gathered experts from diverse fields including computer science, engineering, mathematics, and medicine. The 17 selected papers, chosen from 33 submissions, showcase the latest advancements in techniques and applications for understanding and interpreting visual data from the eye. This collection reflects the interdisciplinary nature of modern ophthalmic research and its reliance on sophisticated computational methods.

The proceedings of the OMIA workshop, as part of the larger MICCAI conference, are expected to be a valuable resource for researchers and practitioners in the field of ophthalmic image analysis. The selection of papers from a competitive review process indicates a high standard of presented work. The interdisciplinary nature of the workshop suggests a broad range of perspectives and methodologies will be covered, contributing to the ongoing development of AI and computational tools for eye care. This collection will likely serve as a key reference for the latest research trends and challenges in this specialized area.