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The Immunoendocrinology of Estrophilin.- Nuclear Binding of the Estrogen Receptor: Heterogeneity of Sites and Uterotropic Response.- The Specific Binding of Estradiol to the Nuclear Matrix.- Heterogeneity of Nuclear Glucocorticoid Receptor Interactions.- Estrogen Control of Progesterone Receptor Induction in Human Breast Cancer: Role of Nuclear Estrogen Receptor.- Estrogen and Antiestrogen Action: Studies in Reproductive Target Tissues and Tumors.- Inhibition of Cell Division and Stimulation of Progesterone Receptor Synthesis in Rat Oestrogen Target Tissues by Non-Steroidal Antioestrogens.- Steroid Hormone Regulation of Uterine Peroxidase Activity.- Progesterone Suppression of the Estradiol Receptor in the Reproductive Tract of Macaques, Cats, and Hamsters.- Regulation and Function of Estrogen and Progesterone Receptor Systems.- Effects of Progestins on the Progesterone Receptor in Guinea Pig Uterus.- The Use of Medroxyprogesterone Acetate to Study Progestin Receptors in Immature, Pregnant, and Adult Rabbit Uterus.- Circannual Rhythms in Progesterone Receptor Levels and Functions.- In vivo Metabolism and Binding of 6?-Methyl-progesterone; A Progestin with Anti-Androgenic and Synandrogenic Activities.- Factors Regulating the Androgenic Action of Progestins in Mouse Kidney.- The Role of Ligand-Binding as a Determinant of the Structure and Activation of the Estrogen Receptor.- Structural Relationships Between the Chick Oviduct Progesterone Receptor A and B Proteins.- Characterization of the Avian Progesterone Receptor through the Use of Inhibitors.- Glucocorticoid Receptor Inactivation and Activation by Phosphorylation Mechanisms.- Glucocorticoid Receptor Cleavage by Leupeptin-Sensitive Enzymes in Rat Kidney Cytosol.- Aspects of Steroid Hormone Target-Cell Interactions.- Studies on the Mechanism of Estradiol Uptake by Rat Uterine Cells and on Estradiol Binding to Uterine Plasma Membranes.- Heterogeneity of AtT-20 Cell Glucocorticoid Binding Sites: Evidence for a Membra
This book investigates the complex mechanisms by which steroid hormones interact with their cellular receptors to regulate gene expression and physiological processes. It compiles research on the binding, heterogeneity, and functional roles of estrogen, progesterone, and glucocorticoid receptors across various tissues and species. The text explores how these interactions influence cellular responses, including cell division, enzyme activity, and receptor induction, drawing on studies of reproductive tissues, tumors, and kidney cytosol.
This collection of research papers offers a deep dive into the intricate world of steroid hormone receptor systems. The detailed studies presented suggest a focus on the molecular and cellular mechanisms underlying hormone action, likely appealing to researchers and advanced students in endocrinology, biochemistry, and molecular biology. The breadth of topics, from receptor heterogeneity to specific regulatory pathways, indicates a comprehensive overview of the field as it stood at the time of publication.
Page Count:
500
Publication Date:
2014-01-15
Publisher:
Springer My Copy UK
ISBN-10:
1475765908
ISBN-13:
9781475765908