This volume presents the refined outcomes of the 16th International Workshop on Information Security Applications (WISA 2015), focusing on critical advancements in digital defense. The workshop, held in August 2015 on Jeju Island, Korea, brought together researchers to discuss the latest challenges and solutions in information security. This collection features 35 thoroughly vetted papers, selected from a pool of 78 submissions, offering deep insights into various facets of security, from hardware vulnerabilities to the emerging threats in the Internet of Things.

This collection of revised papers from WISA 2015 offers a comprehensive overview of the state of information security research in 2015. The rigorous selection process, with 35 papers chosen from 78 submissions, suggests a high standard of presented work. The topical organization, covering areas from hardware security and cryptography to IoT and network security, indicates a broad yet focused scope for researchers in the field. The proceedings are likely to be of significant interest to academics and practitioners seeking to understand the security landscape and emerging threats.