This text investigates the fundamental genetic principles that govern the inheritance of traits in domestic dogs and how these principles apply to the practice of selective breeding. The authors, Malcolm B. Willis (often associated with this seminal work) and Margaret N. Fraser Burns, synthesize biological data and practical breeding experience to provide a framework for understanding canine heredity. They argue that successful breeding outcomes rely on a rigorous application of genetic theory rather than mere intuition or aesthetic preference.

Experts and breeders frequently cite this work as a foundational text for understanding the biological mechanics of canine reproduction. Readers often note the technical density of the prose, which requires a basic understanding of biological concepts to fully grasp the breeding methodologies presented.