This text investigates the phenomenon of polymorphism in molecular crystals, specifically addressing how multiple crystal structures for a single chemical substance influence material properties. Joel Bernstein, a recognized authority in crystallography, synthesizes decades of research to provide a comprehensive framework for understanding why organic molecules adopt different structural forms. The book bridges the gap between theoretical chemistry and practical applications in industries ranging from pharmaceuticals to high-performance dyes.

Experts in the field of materials science and chemistry identify this monograph as a foundational resource for understanding the complexities of molecular crystal structures. Readers frequently note the technical density of the prose, which is tailored specifically for researchers and advanced students requiring a rigorous academic overview of the subject.