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Polypeptide hormones play a central role in the regulation of biological processes from the minute-to-minute control of vital functions to the programming of birth, development, reproduction, and ageing. The first of a two-volume work on the methods of study used in this field, Peptide Hormone Secretion focuses on the isolation of polypeptide hormones and their identification and structural analysis, the development of sensitive bioassay and immunoassay techniques, and tissue localization of peptide hormones and their encoding MRNAs, as well as techniques for characterization of peptide hormone receptors. Ideal for graduate students and researchers, the book includes coverage of the general principles and strategies that the methods are based on, so the techniques will have a wide application to biologically active peptides involved in neurotransmission, growth regulations, differentiation, and vasoregulation.
This volume investigates the methodological frameworks required to isolate, identify, and analyze the secretion and characterization of polypeptide hormones. Authors J. C. Hutton and K. Siddle provide a comprehensive technical manual designed for graduate students and professional researchers. The text synthesizes experimental strategies for studying biological processes, ranging from immediate vital functions to long-term developmental programming.
What You Will Find
Experts identify this work as a foundational technical resource for laboratory researchers focusing on endocrinology and molecular biology. Readers frequently note the high density of the procedural information, which serves as a practical guide for applying these methods to diverse areas of biological study.
Page Count:
368
Publication Date:
1990-12-27
Publisher:
IRL Press
ISBN-10:
0199630690
ISBN-13:
9780199630691
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