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Although most often considered in terms of the generation of action potentials, there are several other electrical, metabolic and ionic correlates of neuronal activity. This book draws together, in a single volume, ten different facets of the activity of nerve cells. There are chapters on the monitoring of extra-cellular unit activity, intracellular voltage and current clamping, patch clamping, video-imaging, in vivo voltammetry, intracerebral dialysis, antibody microprobes, 2-deoxyglucose uptake, intracellular fluorescence and ion-selective electrodes. The techniques described range from the well-established to the experimental. In each case the chapters include up-to-date information, methodological tips and detailed protocols allowing the reader to follow each method in a stepwise fashion. The wide range of techniques in the book should be of interest to neuroscientists, whether concerned with traditional or novel indices on neuronal function.
This volume investigates the diverse electrical, metabolic, and ionic correlates of neuronal activity by providing a comprehensive methodological framework for their measurement. Author J. A. Stamford compiles contributions from experts to address the challenge of monitoring nerve cell function beyond simple action potentials. The text serves as a technical resource, bridging the gap between established laboratory practices and emerging experimental techniques in neurobiology.
What You Will Find
Experts and researchers in the field of neuroscience frequently cite this work as a reliable technical reference for laboratory protocols. The text is noted for its practical utility, providing stepwise instructions that are accessible to both established neuroscientists and those exploring novel indices of neuronal function.
Page Count:
320
Publication Date:
1992-03-19
Publisher:
IRL Press
ISBN-10:
019963243X
ISBN-13:
9780199632435
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