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An important milestone in medicine has been the recent completion of the Human Genome Project. The identification of 30,000 genes and their regulatory proteins provides the framework for understanding the metabolic basis of disease. This advance has also laid the foundation for a broad range of genomic tools that have opened the way for targeted genetic testing in a number of medical disorders. This book is designed to be the first major text to discuss genomics-based advances in disease susceptibility, diagnosis, prognostication,and prediction of treatment outcomes in various areas of medicine. After building a strong underpinning in the basic concepts of genomics, the authors of this book, all leaders in the field, proceed to discuss a wide range of clinical areas and the applications now afforded by genomic analysis.
How does the completion of the Human Genome Project transform the clinical approach to disease diagnosis, prognosis, and treatment? The authors, David Weatherall and Dhavendra Kumar, leverage their extensive expertise in medical genetics to synthesize the transition from basic genomic research to practical clinical application. By establishing a foundational framework of gene identification and protein regulation, the text argues that genomic tools are now essential for predicting patient outcomes and managing complex medical disorders.
What You Will Find
Experts recognize this work as a foundational text for clinicians and researchers seeking to bridge the gap between genomic research and bedside medicine. Readers frequently note the academic density of the prose, which serves as a rigorous reference for those specializing in medical genetics.
Page Count:
672
Publication Date:
2008-01-01
Publisher:
Oxford University Press
ISBN-10:
0199720053
ISBN-13:
9780199720057
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