
RNA viruses provide unique insights into the patterns and processes of evolutionary change in real time. The study of viral evolution is especially topical given the growing awareness that emerging and re-emerging diseases (most of which are caused by RNA viruses) represent a major threat to public health. However, while the study of viral evolution has developed rapidly in the last 30 years, relatively little attention has been directed toward linking work on the mechanisms of viral evolution within cells or individual hosts, to the epidemiological outcomes of these processes. This novel book fills this gap by considering the patterns and processes of viral evolution across their entire range of spatial and temporal scales. The Evolution and Emergence of RNA Viruses provides a comprehensive overview of RNA virus evolution, with a particular focus on genomic and phylogenetic approaches. This is the first book to link mechanisms of viral evolution with disease dynamics, using high-profile examples in emergence and evolution such as influenza, HIV, dengue fever, and rabies. It also reveals the underlying evolutionary processes by which emerging viruses cross species boundaries and spread in new hosts.
This book investigates the fundamental mechanisms of RNA virus evolution and how these processes drive the emergence and spread of infectious diseases across various scales. Edward C. Holmes, a prominent researcher in viral evolution, synthesizes genomic and phylogenetic data to bridge the gap between molecular-level viral changes and large-scale epidemiological outcomes. The text argues that understanding the evolutionary dynamics of these viruses is critical for predicting and managing future disease outbreaks in human and animal populations.
What You Will Find
Scope Limits
Experts recognize this work as a foundational text that successfully connects molecular evolutionary biology with practical epidemiological concerns. Readers frequently note the technical density of the prose, which is best suited for advanced students and researchers in the biological sciences.
Page Count:
266
Publication Date:
2009-01-01
Publisher:
Oxford University Press, USA
ISBN-10:
019154941X
ISBN-13:
9780191549410
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