This text investigates the methodologies and theoretical frameworks required to accurately assign structures to gas-phase ions within the field of mass spectrometry. The authors, Christiane Aubry, John L. Holmes, and Paul A. Mayer, synthesize four decades of research to provide a comprehensive guide for analytical chemists. By integrating experimental techniques with computational chemistry, the book establishes a rigorous protocol for identifying ions containing carbon and various heteroatoms.

Experts recognize this work as a foundational reference for researchers engaged in mass spectrometry and structural identification. Readers frequently note the technical density of the prose, which serves as a practical manual for those applying theoretical calculations to experimental data.