Sallie McBride, a socialite thrust into the role of superintendent at the John Grier Home, must navigate the chaotic demands of managing an orphanage while contending with the cynical, sharp-tongued physician Dr. Robin MacRae. Sallie attempts to modernize the institution and improve the lives of the children, facing resistance from outdated administrative practices and the constant, prickly opposition of the doctor she nicknames 'Dear Enemy.' The narrative unfolds through a series of letters written by Sallie to her friends, providing an intimate look at her personal growth and the evolving dynamics within the home. Her objective is to transform the orphanage into a place of genuine care, a goal that forces her to confront her own prejudices and the rigid social structures of her time.

This work is widely regarded as a charming and witty sequel to the author's previous success, maintaining the lighthearted yet socially conscious tone that defines the series. Readers often highlight the cleverness of the letter-writing format, which allows for a candid and humorous exploration of the protagonist's development. The dynamic between Sallie and Dr. MacRae is frequently cited as a highlight, providing a satisfying emotional arc that complements the institutional reform themes. The book remains a staple of early 20th-century literature, appreciated for its blend of romantic comedy and earnest advocacy for children's rights.