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This book reflects the current state of knowledge about the role of microRNAs in the formation and progression of solid tumours. The main focus lies on computational methods and their applications in combination with cutting edge experimental techniques that are used to approach all aspects of microRNA regulation in cancer. The use of high-throughput quantitative techniques makes an integrative experimental and computational approach necessary. This book will be a resource for researchers starting out with microRNA research, but is also intended for the experienced researcher who wants to incorporate concepts and tools from systems biology and bioinformatics into his work. Bioinformaticians and modellers are provided with a general perspective on microRNA biology, and the state-of-the-art in computational microRNA biology.
This book investigates the intricate regulatory mechanisms of microRNAs in the development and advancement of solid tumors. It synthesizes current knowledge, emphasizing the synergy between computational methods and advanced experimental techniques essential for understanding microRNA regulation in cancer. The necessity of integrating systems biology and bioinformatics is highlighted due to the adoption of high-throughput quantitative methods. The work aims to serve as a foundational resource for new researchers while offering experienced scientists tools to incorporate computational approaches into their studies, and provides bioinformaticians with an overview of microRNA biology and computational strategies.
The book is positioned as a vital resource for researchers entering the field of microRNA, offering foundational knowledge and practical computational tools. It also caters to experienced researchers seeking to integrate systems biology and bioinformatics into their work on cancer regulation. Bioinformaticians and modelers are expected to find value in the comprehensive overview of microRNA biology and the current landscape of computational approaches. The text aims to bridge the gap between experimental biology and computational analysis in the study of microRNAs in cancer.
Page Count:
360
Publication Date:
2016-01-01
ISBN-10:
9402400796
ISBN-13:
9789402400793
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