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Hormonal carcinogenesis is an important and controversial area of current research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? How do genetic factors influence hormone-related cancer risk? Hormones, Genes, and Cancer addresses these questions. Over the past few decades, cancer research has focused on external environmental causes(e.g., tobacco smoke, viruses, asbestos). With the advent of new genetic sequencing techniques, we are just now beginning to understand how the body's internal environment(i.e., the hormones and growth factors that determine normal development) influences cancer etiology and prevention. From molecular insights to clinical analyses, this volume provides state-of-the-art information on the complex interactions between hormones and genes and cancer. The epidemiology and molecular endocrinology of prostate, breast, uterine, ovarian and testicular cancer are detailed in this timely treatise.
This volume investigates whether hormones function as primary carcinogens and how genetic factors modulate the risk of hormone-related cancers. The authors, Brian E. Henderson, Bruce Ponder, and Ronald K. Ross, synthesize decades of research to shift the focus from external environmental factors to the body's internal hormonal environment. By integrating molecular insights with clinical epidemiology, the text provides a framework for understanding the etiology of various reproductive and endocrine-related cancers.
What You Will Find
Experts recognize this work as a foundational text for understanding the intersection of endocrinology and oncology. Readers frequently note the technical density of the prose, which is intended for medical professionals and researchers in the field of cancer biology.
Page Count:
484
Publication Date:
2001-04-15
Publisher:
Oxford University Press
ISBN-10:
0195135768
ISBN-13:
9780195135763
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