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Studies Of Evolution At The Molecular Level Have Experienced Phenomenal Growth In The Last Few Decades, Due To Rapid Accumulation Of Genetic Sequence Data, Improved Computer Hardware And Software, And The Development Of Sophisticated Analytical Methods. The Flood Of Genomic Data Has Generated An Acute Need For Powerful Statistical Methods And Efficient Computational Algorithms To Enable Their Effective Analysis And Interpretation. Molecular Evolution: A Statistical Approach Presents And Explains Modern Statistical Methods And Computational Algorithms For The Comparative Analysis Of Genetic Sequence Data In The Fields Of Molecular Evolution, Molecular Phylogenetics, Statistical Phylogeography, And Comparative Genomics. Written By An Expert In The Field, The Book Emphasizes Conceptual Understanding Rather Than Mathematical Proofs. The Text Is Enlivened With Numerous Examples Of Real Data Analysis And Numerical Calculations To Illustrate The Theory, In Addition To The Working Problems At The End Of Each Chapter. The Coverage Of Maximum Likelihood And Bayesian Methods Are In Particular Up-to-date, Comprehensive, And Authoritative. This Advanced Textbook Is Aimed At Graduate Level Students And Professional Researchers (both Empiricists And Theoreticians) In The Fields Of Bioinformatics And Computational Biology, Statistical Genomics, Evolutionary Biology, Molecular Systematics, And Population Genetics. It Will Also Be Of Relevance And Use To A Wider Audience Of Applied Statisticians, Mathematicians, And Computer Scientists Working In Computational Biology.
This text investigates the statistical and computational methodologies required to analyze genetic sequence data within the framework of evolutionary biology. Ziheng Yang, a recognized authority in computational phylogenetics, synthesizes complex mathematical models into an accessible format for researchers. The book focuses on the application of maximum likelihood and Bayesian inference to genomic data, providing a structured approach to interpreting evolutionary history through molecular sequences.
What You Will Find
Scope Limits
Experts identify this work as a foundational text for graduate students and professionals in bioinformatics and statistical genomics. Readers frequently note the balance between conceptual clarity and the technical rigor required for modern computational analysis.
Page Count:
528
Publication Date:
2014-01-01
Publisher:
Oup Oxford
ISBN-10:
0191023302
ISBN-13:
9780191023309
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